Club de Revistas de Dermatopatología. Jueves 18 de abril 2013
14.04.2013 08:30
Psoriasis: Clinical Features and Pathology
McCall, Calvin O.January/February 2011 - Volume 16 - Issue 1 - pp 2-9
Psoriasis is a chronic, relapsing inflammatory disease potentially affecting all areas of the skin, nails, and mucous membranes. Psoriasis vulgaris is the classic presentation, but there are multiple var- iants of the disease. When the presentation is Btypical,[ there is little difficulty arriving at a clinical diagnosis and a cutaneous biopsy may not be obtained. The pathologist is most often involved in establishing the diagnosis of psoriasis when there is an atypical clinical presentation, the patient has a less common variant of the disease, or the disease has been partially treated or altered by secondary changes. In these cases, the pathologic findings may be altered. Familiarity with the features of psoriasis vulgaris and the less common variants of psoriasis enables the pathologist to recognize the features of psoriasis even when they are incomplete or partially obscured.This review will present the clinical and pathologic findings of psoriasis vulgaris and the variants of psoriasis, present the differential diagnosis of psoriasis, and discuss the importance of pathologic findings in the evolving pathophysiology and treatment of psoriasis.
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