Cutaneous physiological signs of pregnancy
Ver www.dermquest.com/expert_opinions/clinical_updates/cutaneous_physiological_signs_of_pregnancy.html
|
Pigmentary changes
Non-facial hyperpigmentation Melasma |
|
Vascular changes Spider telangiectasias Palmar erythema
Venous hypertension signs
Vasomotor instability
Vascular proliferation |
|
Structural changes Striae gravidarum Molluscum fibrosum gravidarum |
|
Adnexal changes
Hair
Nails
Glands |
Table 1. Physiologic changes of the skin and the mucosa during pregnancy.
Pigmentary changes
As multiple signs occur in a large percentage of pregnant women, physiological changes of the skin during gestation are important to recognize and differentiate from diseases in order to reassure women and avoid unnecessary investigations (Table 1).
The three major mechanistic factors that induce the development of these changes are (i) an increase in circulating hormones secreted by the ovaries and/or placenta, including estrogens, progesterone, human placental lactogen and placental-like growth factor (PlGF), (ii) intravascular volume expansion, and (iii) compression from the enlarging uterus............
